Synthetic communications

Asymmetric synthesis of furo-pyrrolo-isoquinoline and furo-indolizino-indole derivatives via a diastereoselective N-acyliminium ion cyclization

Y Sup Lee, J Yeol Lee, H Park

文献索引：Lee, Yong Sup; Lee, Jae Yeol; Park, Hokoon Synthetic Communications, 1997 , vol. 27, # 16 p. 2799 - 2812

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被引用次数: 7

摘要

ABSTRACT Asymmetric synthesis of hro-pyrrolo-isoquinoline and hro- indolizino-indole derivatives via a diastereoselective N-acyliminium ion cyclization of chiral enamides is described. The requisite chiral enamides were prepared from readily available L-malic acid. ... The isoquinoline and indole alkaloids are abundant in plant products' and ... N-acyliminium ion cyclization, although well known, have only recently been ... Spe~kamp,~ and others,436 such cyclizations ...