The Journal of organic chemistry

Chloroperoxidase as enantioselective epoxidation catalyst: an efficient synthesis of (R)-(-)-mevalonolactone

FJ Lakner, LP Hager

文献索引：Lakner, Frederick J.; Hager, Lowell P. Journal of Organic Chemistry, 1996 , vol. 61, # 11 p. 3923 - 3925

全文：HTML全文

被引用次数: 116

摘要

As an important intermediate in biosynthetic pathways leading to sterols, terpenes, corotenoids, and other pentanoid compounds, 1 (R)-(-)-mevalonic acid or especially its lactone form (4) has been a synthetic target of considerable interest. A number of chemical methodologies have been described, the most popular of which involves asymmetric induction provided by Sharpless epoxidation of a suitable allylic alcohol. 2 Chiral pool ...