Metal ion induced allosteric transition in the catalytic activity of an artificial phosphodiesterase

S Takebayashi, M Ikeda, M Takeuchi…

文献索引：Takebayashi, Shinji; Ikeda, Masato; Takeuchi, Masayuki; Shinkai, Seiji Chemical Communications, 2004 , # 4 p. 420 - 421

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摘要

The design of artificial allosteric systems is of great significance for regulating the catalytic activities and complexation properties of artificial receptors. 1 We have been interested in the exploitation of homotropic allosteric systems, which show the nonlinear amplification of binding events and chemical signals. 2 This phenomenon is useful to control the activities of an artificial receptor in an OFF–ON switching manner at a threshold condition. 1,2 Allosteric molecular ...