Tetrahedron letters

Single-flask polyfunctionalization of the imidazole ring; a streamlined route to the antitumor agent carmethizole

BH Lipshutz, W Hagen

文献索引：Lipshutz, Bruce H.; Hagen, William Tetrahedron Letters, 1992 , vol. 33, # 40 p. 5865 - 5868

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被引用次数: 53

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Three sequential treatments of an N-protected tribromoimidazole with n-BuLi / electrophile in a 1-pot process leads to N-protected 2,4,5-trisubstituted imidazoles. The method can be applied to the preparation of the immediate of carmethizole. ... Trisubstituted imidazoles via ...