Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Three sequential treatments of an N-protected tribromoimidazole with n-BuLi / electrophile in a 1-pot process leads to N-protected 2,4,5-trisubstituted imidazoles. The method can be applied to the preparation of the immediate of carmethizole. ... Trisubstituted imidazoles via ...