Benzo [c] furans are a class of interesting and highly reactive compounds that readily undergo Diels–Alder cycloaddition with dienophiles to restore their aromaticity. Initially, the s- tetrazine approach established by Warrener was chosen for the synthesis of the title molecule. However, it was discovered that the rate of production of isobenzofuran from this approach was too slow to react with the fugitive arynes. Consequently, an alternative route ...
