Practical synthesis of new and highly efficient ligands for the Suzuki reaction of aryl chlorides

A Zapf, R Jackstell, F Rataboul, T Riermeier…

文献索引：Zapf, Alexander; Jackstell, Ralf; Rataboul, Franck; Riermeier, Thomas; Monsees, Axel; Fuhrmann, Christa; Shaikh, Nadim; Dingerdissen, Uwe; Beller, Matthias Chemical Communications, 2004 , # 1 p. 38 - 39

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被引用次数: 139

摘要

A practical synthesis of a novel class of phosphine ligands, phosphino substituted N-aryl pyrroles (PAP ligands), has been developed. These ligands are applied in the palladium- catalyzed coupling of a variety of aryl and heteroaryl chlorides with phenylboronic acid showing exceedingly high turnover numbers at mild reaction temperatures and even at room temperature.