Regioselective palladium-catalyzed arylation of 2-furaldehyde

…, B Glover, E McSorley, A Millar, MH Osterhout…

文献索引：McClure; Glover; McSorley; Millar; Osterhout; Roschangar Organic letters, 2001 , vol. 3, # 11 p. 1677 - 1680

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被引用次数: 122

摘要

An efficient regioselective method for the direct arylation of 2-furaldehyde to provide a range of π-diverse 5-aryl-2-formylfuran derivatives is described. The method employs functionalized aryl halides and a catalytic amount of palladium (II) chloride under relatively mild conditions.