Tetrahedron

Acylation-cyclization of allenes

RW Bates, T Rama-Devi, HH Ko

文献索引：Bates, Roderick W.; Rama-Devi, Thota; Ko, Huei-Huei Tetrahedron, 1995 , vol. 51, # 47 p. 12939 - 12954

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被引用次数: 20

摘要

Allenes bearing a nucleophilic group cyclize on treatment with acyltetracarbonyl cobalt complexes in the presence of mild bases. Various nucleophilic groups and cobalt complexes can be used to give highly functionalized pyrrolidines, cyclopentanes and tetrahydrofurans. Disubstituted allenes may be used in the reaction. 1, 3-disubstituted allenes give products with high stereoselectivity.