European Journal of Organic Chemistry

CuI??Catalyzed Synthesis of Functionalized Terminal Allenes from 1??Alkynes

H Luo, S Ma

文献索引：Luo, Hongwen; Ma, Shengming European Journal of Organic Chemistry, 2013 , # 15 p. 3041 - 3048

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被引用次数: 9

摘要

Abstract Relative to our original protocol that uses CuI (0.5 equiv.), paraformaldehyde (2.5 equiv.), and dicyclohexylamine (1.8 equiv.), a facile and efficient protocol for the gram-scale synthesis of functionalized terminal allenes by using CuI (7.5–10 mol-%), paraformaldehyde (1.6 equiv.), and diisopropylamine (1.4 equiv.) has been developed. This method accommodates different functional groups such as hydroxy or carbonyl, and it also ...