A preparative method has been developed for the synthesis of 1-hydroxy-3-oxo-5,6-dihydro- 3H pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid hydrazide and its derivatives. The results of a study of the antitubercular activity of the synthesized compounds are presented. ... Keywords: 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acids, amidation, hydrazinolysis, antitubercular activity. ... Hydrazine derivatives occupy a special place in the chemotherapy of ...