A new series of substances which block the adrenergic β-receptors

H Corrodi, H Persson, A Carlsson…

文献索引：Corrodi,H. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 751 - 755

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被引用次数: 43

摘要

il series of plienylethanolaniines and phenylpropanolamines with chlorine or alkyl substitution in the benzene nucleus has been synthesized which block adrenergic/3- receptors in mammals. A clear relationship between structure and activity allowed us to synthesize potent P-receptor blockers with or without intrinsic sympathomimetic activity.