il series of plienylethanolaniines and phenylpropanolamines with chlorine or alkyl substitution in the benzene nucleus has been synthesized which block adrenergic/3- receptors in mammals. A clear relationship between structure and activity allowed us to synthesize potent P-receptor blockers with or without intrinsic sympathomimetic activity.
![1-Propanone,2-[(1-methylethyl)amino]-1-(4-methylphenyl)-(9CI) Structure](https://image.chemsrc.com/caspic/472/784076-40-0.png)
