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Inhibitors of tissue-nonspecific alkaline phosphatase: design, synthesis, kinetics, biomineralization and cellular tests

…, R Buchet, D Magne, F Popowycz, M Lemaire

文献索引:Debray, Julien; Lemaire, Marc; Popowycz, Florence Synlett, 2013 , vol. 24, # 1 p. 37 - 40

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被引用次数: 12

摘要

Abstract Chronic kidney disease (CKD) is associated with numerous metabolic and endocrine disturbances, including abnormalities of calcium and phosphate metabolism and an inflammatory syndrome. The latter occurs early in the course of CKD and contributes to