The Journal of Organic Chemistry

Room temperature catalytic amination of aryl iodides

JP Wolfe, SL Buchwald

文献索引：Wolfe, John P.; Buchwald, Stephen L. Journal of Organic Chemistry, 1997 , vol. 62, # 17 p. 6066 - 6068

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被引用次数: 123

摘要

The palladium-catalyzed amination of aryl halides has been shown to be a general method for the formation of aromatic carbon-nitrogen bonds. 1 However, current versions of this method still suffer from the need for relatively high reaction temperatures (65-100 C) which may pose problems for reactions involving thermally sensitive molecules or in situations where it is inconvenient to heat reactions (eg, combinatorial chemistry applications). 2 ...