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" Tert-Amino effect" in heterocyclic synthesis. Formation of N heterocycles by ring-closure reactions of substituted 2-vinyl-N, N-dialkylanilines

W Verboom, DN Reinhoudt, R Visser…

文献索引:Verboom, Willem; Reinhoudt, David N.; Visser, Richard; Harkema, Sybolt Journal of Organic Chemistry, 1984 , vol. 49, # 2 p. 269 - 276

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被引用次数: 95

摘要

5b, c and the (4-morpholiny1) benzeneacetonitrile 7c do not react. The (1-piperidiny1) benzeneacetonitrile 7b yields in refluxing toluene in the presence of zinc chloride the pyrido [l, 2-a] indole 14b and, by HCN elimination, pyrido [l, 2-a] indole 15b. Under these ...