Abstract The formation of a new, dihydrate crystalline form of 5-methyluridine (m 5 U) was selectively induced by a protein additive, antifreeze protein (AFP) in a highly efficient manner (in 10− 6 molar scale, whereas known kinetic additives need 0.1 molar scale). The hemihydrate form (form I, the only previously known crystalline form of m 5 U) and the dihydrate form of m 5 U (form II) obtained herein were characterized using X-ray ...
[Gordon, Gregory E. R.; Bode, Moira L.; Visser, Daniel F.; Lepuru, M. Jerry; Zeevaart, Jacob G.; Ragubeer, Nasheen; Ratsaka, Molala; Brady, Dean; Walwyn, David R. Organic Process Research and Development, 2011 , vol. 15, # 1 p. 258 - 265]