Tetrahedron letters

Arylmethyl phenyl sulfones, a new carbon nucleophile for Mitsunobu-type alkylation

T Tsunoda, K Uemoto, T Ohtani, H Kaku, S Itô

文献索引：Tsunoda, Tetsuto; Uemoto, Kaori; Ohtani, Tomoko; Kaku, Hiroto; Ito, Sho Tetrahedron Letters, 1999 , vol. 40, # 41 p. 7359 - 7362

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被引用次数: 21

摘要

Cyanomethylenetrimethylphosphorane (CMMP), a new Mitsunobu reagent developed recently by the authors, mediated the alkylation of arylmethyl phenyl sulfones with primary and secondary alcohols quite efficiently. Utilizing 3-((phenylsulfonyl) methyl) pyridine, theonelladine D, a unique pyridine alkaloid, was synthesized in excellent yield.