Abstract New procedures have been developed for the synthesis of α-(2-formyl-1 H-pyrrol-1- yl)-substituted carboxylic acids, α-(2-R-aminomethyl-1 H-pyrrol-1-yl)-substituted carboxylic acids, and 1, 2-dihydropyrrolo-[1, 2-a] pyrazin-3 (4 H)-ones on the basis of furfurol and α- amino acids.