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Synthesis of novel GABA uptake inhibitors. 4. 1 Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent …

KE Andersen, JL Sørensen, PO Huusfeldt…

文献索引:Journal of Medicinal Chemistry, , vol. 42, # 21 p. 4281 - 4291

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被引用次数: 43

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The overall general strategy used for the preparation of the new compounds presented in Table 1 was via N-alkylation of the parent cyclic amino acids 1 or 2, 46 with the appropriate ...