Synthesis of Potential Anticancer Agents. XII. 9-Alkyl-6-substituted-purines2

JA Montgomery, C Temple Jr

文献索引：Montgomery; Temple Journal of the American Chemical Society, 1958 , vol. 80, p. 409

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被引用次数: 32

摘要

The 9-n-butyl, 9-cyclopentyl and 9-cyclohexyl analogs of purine, adenine and 6- mercaptopurine have been prepared from the corresponding 9-alkyl-6-chloropurines. The chloropurines and the hypoxanthine analogs were prepared by the reaction of the appropriate 4-alkylamino-5-amino-6-chloropyrimidines with diethoxymethyl acetate and formic acid, respectively.