Acta Chemica Scandinavica

The Preparation of Partially Protected 3-Amino-1-methylpyrazole-5-carboxylic Acids to be Used as Intermediates in the Synthesis of Analogues of Distamycin A

L Ding, L Grehn, U Ragnarsson

文献索引：Ding, Lu; Grehn, Leif; Ragnarsson, Ulf Acta Chemica Scandinavica, 1990 , vol. 44, # 1 p. 75 - 81

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被引用次数: 4

摘要

Partially protected 3-amino-1-methylpyrazole-5-carboxylic acid derivatives have been prepared by a convenient route from 3-amino-1-methylpyrazole. The structures of these compounds have been correlated with recent work in the field. Such derivatives, blocked on the amino function with tert—butyloxycarbonyl (6) or formyl (8) groups or on the carboxy function with benzyl (4a) or ethyl (4b) groups, should serve as suitable precursors for the ...