Solid-phase synthesis of new saphenamycin analogues with antimicrobial activity

JB Laursen, PC De Visser, HK Nielsen…

文献索引：Laursen, Jane B.; De Visser, Peter C.; Nielsen, Henrik K.; Jensen, Knud J.; Nielsen, John Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 171 - 175

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被引用次数: 20

摘要

An array of 12 new saphenamycin analogues modified at the benzoate moiety was synthesized on solid support. Synthesis commenced with a chemoselective anchoring of saphenic acid through the carboxyl group to a 2-chlorotrityl functionalized polystyrene ...