Synthesis of di??amino??salicil and some of its derivatives

W Berends, JM Waisvisz…

文献索引：Berends et al. Recueil des Travaux Chimiques des Pays-Bas, 1955 , vol. 74, p. 1323,1336

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被引用次数: 1

摘要

Abstract From the work of R. Kuhn et al. it appeared that brominated derivatives of salicil have a high anti-bacterial activity in vitro, but that in vivo they show only little activity as a result of serum-binding. Base-substituted phenols are usually bound by serum to a smaller extent. Therefore, an amino-substituted bromo-salicil was synthesized. A water soluble derivative of this compound was also prepared.