Label??Free Detection of Protein–Protein Interactions on Biochips

…, RW Hsieh, GL Greene, M Mrksich

文献索引：Yeo, Woon-Seok; Min, Dal-Hee; Hsieh, Robert W.; Greene, Geoffrey L.; Mrksich, Milan Angewandte Chemie - International Edition, 2005 , vol. 44, # 34 p. 5480 - 5483

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被引用次数: 62

摘要

The recent introduction of protein microarrays is now providing tools for the global profiling of biochemical activities.[1] Snyder and co-workers, for example, used yeast protein chips to identify kinase substrates and lipid-binding proteins.[2] Labaer and co-workers reported self- assembling protein microarrays to map pairwise interactions among 29 human DNA replication proteins.[3] Any application of a protein chip must involve a suitable labeling ...