Tetrahedron

Synthesis of substituted bis (heteroaryl) maleimides

…, V Caubert, J Guillard, MC Viaud-Massuard

文献索引：Dubernet, Mathieu; Caubert, Virginie; Guillard, Jerome; Viaud-Massuard, Marie-Claude Tetrahedron, 2005 , vol. 61, # 19 p. 4585 - 4593

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被引用次数: 76

摘要

Substituted bis (fur-2-yl), bis (fur-3-yl) and bis (thien-2-yl) maleimides with potential antidiabetic properties are described. Their synthesis involves, as a key step, a Suzuki cross- coupling between various boron derivatives and the diiodomaleimides. Therefore, a wide range of substituted symmetric and non-symmetric maleimide derivatives can be prepared.