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Ultrasound??Promoted Reaction of 2??Chlorobenzoic Acids and Aliphatic Amines

…, A Estevez??Braun, AG Ravelo

文献索引:Docampo, Maite L.; Pellon, Rolando F.; Estevez-Braun, Ana; Ravelo, Angel G. European Journal of Organic Chemistry, 2007 , # 24 p. 4111 - 4115

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被引用次数: 10

摘要

Abstract An improvement to the use of DMF as a solvent for the condensation of 2- chlorobenzoic acids with aliphatic primary or secondary amines was described. A number of alkylaminobenzoic acids and dialkylaminobenzoic acids were synthesized in acceptable-to- good yield. The advantages of this procedure include readily available substrates, the use of an inexpensive copper powder without taking any precautions to exclude moisture under ...