Synthesis and in vitro antifungal evaluation of 2-(2, 4-difluorophenyl)-1-[(1 H-indol-3-ylmethyl) methylamino]-3-(1 H-1, 2, 4-triazol-1-yl) propan-2-ols
R Guillon, C Logé, F Pagniez…
文献索引:Journal of Enzyme Inhibition and Medicinal Chemistry, , vol. 26, # 2 p. 261 - 269
... Journal of Enzyme Inhibition and Medicinal Chemistry. ... and accumulation of toxic intermediate sterols, causing increased membrane permeability and inhibition of fungal ... acid residue in Candida albicans sterol 14alpha-demethylase associated with the enzyme activity and ...