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Chem. Pharm. Bull

Human Chorionic Gonadotropin. III. 1'2) Synthesis of a Dotriaconta-peptide corresponding to the C-Terminal Sequence 116—147 of the [if-Subunit of Human …

K KAWASAKI, O TANIZAWAab

文献索引:Kawasaki; Tsuda; et al. Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 9 p. 2699 - 2706

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被引用次数: 4

摘要

A dotriacontapeptide, H-Gln—Asp—Ser—SereSer~ Lys—Ala—Pro---Pro~ Pro~ Ser—Leu— Pro—Ser—Pro—Ser~. 4rg~ Leu~ Pr0—Gly~ Pro—Pro—Asn—Thr—Pro—Ile—Leu——Pro— Gln—Ser—Leu—Pro~—OH, corresponding to the C-terminal sequence 116—147 of hCG— fi proposed by Carlsen et al. was synthesized by stepwise fragment condensation, linking five fragments [Z—Gln «Asp (Ole)—OH, Z—Ser (le)—Ser—Ser—Lys (BOC)-—NHNH2, Z ...