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Molecules

Synthesis and SAR studies of praziquantel derivatives with activity against Schistosoma japonicum

…, LJ Song, X Chen, XR Yin, WH Fan, GP Wang, CX Yu…

文献索引:Wang, Wen-Long; Song, Li-Jun; Chen, Xia; Yin, Xu-Ren; Fan, Wen-Hua; Wang, Gu-Ping; Yu, Chuan-Xin; Feng, Bainian Molecules, 2013 , vol. 18, # 8 p. 9163 - 9178

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被引用次数: 4

摘要

Abstract: The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described. Several of them showed better worm killing activity than praziquantel and could serve as leads for further optimization.