Tetrahedron

The reactions of ureas with glyoxylic acid and methyl glyoxylate

D Ben-Ishai, J Altman, Z Bernstein

文献索引：Ben-Ishai,D. et al. Tetrahedron, 1977 , vol. 33, p. 1191 - 1196

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被引用次数: 12

摘要

The reactions of urea, methylurea and dimethylureas with glyoxylic acid and its methyl ester to give α-substituted hydantoic acid derivatives (4, 5, 6, 7) and substituted allantoic acid derivatives (8) is discussed. The cyclization of the hydantoates and allantoates to 5- substituted hydantoins (11, 12) is also described.