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A method for parallel solid-phase synthesis of iodinated analogues of the CB1 receptor inverse agonist Rimonabant

…, CC Tseng, TC Jones, AD Kohler, GJ Ellames

文献索引:Spivey, Alan C.; Martin, Laetitia J.; Noban, Catherine; Jones, Teyrnon C.; Ellames, George J.; Kohler, Andrew D. Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 5-6 p. 281 - 285

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被引用次数: 11

摘要

A method for the parallel solid-phase synthesis (SPS) of iodinated analogues of Sanofi- Aventis' type 1 cannabinoid (CB1) receptor inverse agonist rimonabant (acomplia) has been developed. The method allows the synthesis of a range of C3 amide/hydrazide derivatives