A method for parallel solid-phase synthesis of iodinated analogues of the CB1 receptor inverse agonist Rimonabant

…, CC Tseng, TC Jones, AD Kohler, GJ Ellames

Index: Spivey, Alan C.; Martin, Laetitia J.; Noban, Catherine; Jones, Teyrnon C.; Ellames, George J.; Kohler, Andrew D. Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 5-6 p. 281 - 285

Full Text: HTML

Citation Number: 11

Abstract

A method for the parallel solid-phase synthesis (SPS) of iodinated analogues of Sanofi- Aventis' type 1 cannabinoid (CB1) receptor inverse agonist rimonabant (acomplia) has been developed. The method allows the synthesis of a range of C3 amide/hydrazide derivatives