Tetrahedron Letters

Organocatalytic synthesis of amides from nitriles via the Ritter reaction

S Khaksar, E Fattahi, E Fattahi

文献索引：Khaksar, Samad; Fattahi, Eskandar; Fattahi, Esmail Tetrahedron Letters, 2011 , vol. 52, # 45 p. 5943 - 5946

全文：HTML全文

被引用次数: 27

摘要

A simple, inexpensive, environmentally friendly, and efficient route for the synthesis of a wide variety of amides in high yields via the Ritter reaction of alcohols with nitriles has been demonstrated. Pentafluorophenyl ammonium triflate (PFPAT) is used as an organocatalyst and is air-stable, cost-effective, easy to handle, and easily removed from the reaction mixtures.