Synthesis

Synthesis of natural fimbrolides

KP Haval, NP Argade

文献索引：Haval, Kishan P.; Argade, Narshinha P. Synthesis, 2007 , # 14 p. 2198 - 2202

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被引用次数: 12

摘要

Abstract Starting from citraconic anhydride, a three-step approach to fimbrolide congener is reported by taking the advantage of a regioselective Grignard reaction with an anhydride, followed by a dehydrative cyclization and double bromination-dehydrobromination sequence. Starting from N-(4-tolyl) maleimide, an eight-step synthesis of two natural fimbrolides is reported with good yields via the synthesis of requisite butylmaleic ...