Abstract 6-Deoxy-6-mycoloylamino-α, α-trehalose, a biologically active derivative of 6, 6′-di- O-mycoloyl-α, α-trehalose (TDM), and N-acetyl-6-O-(aminoacyl)-muramoyl dipeptide (MDP) were joined chemically by a succinic acid unit. The compounds synthesized showed activities that are characteristic of both TDM and MDP.
[Gavande, Navnath; Kim, Hye-Lim; Doddareddy, Munikumar R.; Johnston, Graham A. R.; Chebib, Mary; Hanrahan, Jane R. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 4 p. 402 - 407]
