A new sunscreen of the cinnamate class: synthesis and enzymatic hydrolysis evaluation of glyceryl esters of p-methoxycinnamic acid

…, GM Dellamora-Ortiz, JCS Gonçalves

文献索引：De Freitas, Zaida Maria Faria; Dos Santos, Elisabete Pereira; Da Rocha, Joao Ferreira; Dellamora-Ortiz, Gisela Maria; Goncalves, Jose Carlos Saraiva European Journal of Pharmaceutical Sciences, 2005 , vol. 25, # 1 p. 67 - 72

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被引用次数: 13

摘要

Glyceryl esters of p-methoxycinnamic acid, 1, 3-dipalmitoyl-2-p-methoxycinnamoyl-1, 2, 3- propanetriol and 1, 3-dioctanoyl-2-p-methoxycinnamoyl-1, 2, 3-propanetriol were synthesised in an attempt to increase substantivity and decrease eventual undesirable effects of sunscreens of this class. To assess if the glyceryl esters could present a higher stability towards hydrolysis by lipases in the stratum corneum, hydrolysis rates were ...