Direct C2-trifluoromethylation of indole derivatives catalyzed by copper acetate

…, H Egami, T Nagi, J Chae, Y Hamashima, M Sodeoka

文献索引：Shimizu, Ryo; Egami, Hiromichi; Nagi, Tatsuya; Chae, Jungha; Hamashima, Yoshitaka; Sodeoka, Mikiko Tetrahedron Letters, 2010 , vol. 51, # 45 p. 5947 - 5949

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被引用次数: 94

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Direct C2-selective trifluoromethylation of indole derivatives was achieved with Togni's hypervalent iodine reagent and CuOAc as a catalyst in MeOH under mild conditions, affording the desired C2-trifluoromethylated indoles in good yield (up to 90%).