Mycobacterium tuberculosis H37Rv3377c encodes the diterpene cyclase for producing the halimane skeleton

…, T Okamura, T Sato, T Dairi, T Hoshino

文献索引：Nakano, Chiaki; Okamura, Tomoo; Sato, Tsutomu; Dairi, Tohru; Hoshino, Tsutomu Chemical Communications, 2005 , # 8 p. 1016 - 1018

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被引用次数: 38

摘要

The cloning and functional expression of Mycobacterium tuberculosis Rv3377c in Escherichia coli revealed that this gene encodes the diterpene cyclase for producing (+)-5 (6), 13-halimadiene-15-ol, which accepts geranylgeranyldiphosphate as the intrinsic substrate.