Tetrahedron letters

Conjugate addition of imidazolines: a protocol for 1, 4-addition to enones and other acceptors

RCF Jones, SC Hirst

文献索引：Jones, Raymond C. F.; Hirst, Simon C. Tetrahedron Letters, 1989 , vol. 30, # 39 p. 5361 - 5364

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被引用次数: 43

摘要

Abstract The enaminoester 1-benzyl-2-ethoxycarbonylmethyleneimidazolidine reacts with α, β-enones and other Michael acceptors to give 1, 4-adducts; removal of the ethoxycarbonyl group completes overall conjugate addition of the imidazoline α-anion (which itself adds 1, 2 to enones), and hydrolysis affords carboxylic acids.