Potential tumor-or organ-imaging agents. 26. Polyiodinated 2-substituted triacylglycerols as hepatographic agents

…, SW Schwendner, RE Counsell

文献索引：Weichert; Longino; Schwendner; Counsell Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1674 - 1682

被引用次数: 18

摘要

A series of w-(3-amino-2, 4, 6-triiodophenyl) alkanoic acids and the corresponding 1, 3- dipalmitoylglycerol 2-[~-(3-amino-2, 4, 6-triiodophenyl) alkanoates] were synthesized, radioiodinated with iodine-125, and evaluated for their ability to selectively localize in the liver for potential use as hepatographic imaging agenta. Acid analogues Id and le afforded relatively high levels of radioactivity in the liver (45 and 49% injected dose) 5 min after ...

1664-54-6

3-(3-氨基苯基)丙酸

~64%

~85%

~62%

Peroxisome proliferator-activated receptor agonists with phe...

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Oxalylmethylenephosphoranes. 2. Synthesis and biological act...

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Aggregation-induced fluorescence behavior of triphenylamine-...

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Push–pull structures with a pyrazine core and hexatriene cha...

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