Journal of the American Chemical Society

The Gilman reagent Ph2CuLi and higher-order Ph3CuLi2: carbon-13 and lithium-6 NMR in dimethyl sulfide

SH Bertz, G Dabbagh

文献索引：Bertz, Steven H.; Dabbagh, Gary Journal of the American Chemical Society, 1988 , vol. 110, p. 3668 - 3670

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被引用次数: 53

摘要

Higher order organocupratesZa have recently joined the classical Gilman reagentsZb at the forefront of synthetic methodology. While “Me3CuLi2” had been postulated as a reactive intermediate, Lipshutz et al. showed by means of 'H and'Li NMR that the addition of MeLi to Me, CuLi does not form a higher order species, Le., the reagent is merely Me2CuLi+ MeLi? In contrast, to within the limits of NMR detection, free MeLi is not present in the higher ...