Preparation and application of odorless 1, 3-propanedithiol reagents

M Matoba, T Kajimoto, K Nishide, M Node

文献索引：Matoba, Manabu; Kajimoto, Tetsuya; Nishide, Kiyoharu; Node, Manabu Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 1 p. 141 - 146

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被引用次数: 18

摘要

2-Dodecyl-1, 3-propanedithiol (2a) was prepared without a malodorous procedure as an odorless reagent that was usable in place of 1, 3-propanedithiol (1) in organic reactions, eg, in the reduction of azides and protection of carbonyl groups. The 1, 3-dithioacetals obtained in the latter reaction were effectively reduced to methylene with Raney nickel and reconverted to the original carbonyl compounds by hydrolysis with N-bromosuccinimide in ...