Synlett

Convenient Cleavage of Water-Insoluble Allylic Substrates in the Presence of Per (2, 6-di-O-methyl)-β-cyclodextrin

R Widehem, T Lacroix, H Bricout, E Monflier

文献索引：Widehem, Rodrigue; Lacroix, Thibaut; Bricout, Herve; Monflier, Eric Synlett, 2000 , # 5 p. 722 - 724

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被引用次数: 19

摘要

Abstract: The removal of allylic protecting groups promoted by a water soluble palladium complex of the trisulfonated triphenylphosphine is achieved in very high yields (95-100%) on a wide range of water-insoluble substrates in a genuine two-phase system by using the per (2, 6-di-O-methyl)-b-cyclodextrin as inverse phase transfer catalyst. The catalytic activities were up to 1000 times higher than those observed without cyclodextrin. Key ...