Tetrahedron letters

The Heck reaction in the presence of molecular oxygen

T Hosokawa, T Kamiike, SI Murahashi, M Shimada…

文献索引：Hosokawa, Takahiro; Kamiike, Taisuke; Murahashi, Shun-Ichi; Shimada, Mamoru; Sugafuji, Toshihiro Tetrahedron Letters, 2002 , vol. 43, # 51 p. 9323 - 9325

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被引用次数: 13

摘要

Palladium-catalyzed reaction of CH2 C (R) COOMe (R= H or CH2OH) with PhI in the presence of NEt3 under O2 induces the oxidative dealkylation of NEt3, affording either methyl 3-diethylaminopropionate (3) or methyl (Z)-2-benzyl-3-(N, N′-diethylamino) propenate (6), in case of R= H or R= CH2OH, respectively.