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Tetrahedron Letters

Solid-phase synthesis of 3-hydroxymethyl isoxazoles via resin bound nitrile oxides

E Cereda, A Ezhaya, M Quai, W Barbaglia

文献索引:Cereda, Enzo; Ezhaya, Antoine; Quai, Monica; Barbaglia, Walter Tetrahedron Letters, 2001 , vol. 42, # 30 p. 4951 - 4953

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被引用次数: 17

摘要

Solid-phase synthesis is gaining more importance since its scope has been extended from the preparation of peptide compounds, as originally pioneered by Merrifield, to the synthesis of small organic molecules. 1 The development of new synthetic procedures suited to solid-phase synthesis continues to be a major focus for chemistry. The methods amenable to automation for the parallel production of compounds are of particular value. ... A small library of 3-hydroxymethyl-4,5- ...