Facile Baylis-Hillman reaction of substituted 3-isoxazolecarbaldehydes: The impact of a proximal heteroatom within a heterocycle on the acceleration of the reaction
... To substantiate this hypothesis on the basis of experimental evidence, the synthesis and Baylis-Hillman reaction of substituted 3-isoxazolecarbaldehydes ... Calcd for C 15 H 15 NO 4 : C, 65.92; H, 5.53; N, 5.13. ... 2-[Hydroxy-(5- p -tolylisoxazol-3-yl)methyl]acrylic Acid Ethyl Ester (7b). ...