Enantioselective Copper-Catalyzed Formal [4+ 2] Cycloaddition of o-Aminophenol Derivatives with Propargylic Esters for Synthesis of Optically Active 3, 4-Dihydro-2 …
The first copper-catalyzed asymmetric formal [4+ 2] cycloaddition of o-aminophenol derivatives with propargylic esters as the bis-electrophilic C2 synthons for the stereoselective construction of chiral 2, 3, 4-trisubstituted 2 H-1, 4-benzoxazines bearing an