Tetrahedron Letters

Direct and chemoselective conversion of carboxylic acids into aldehydes

T Fujisawa, T Mori, S Tsuge, T Sato

文献索引：Fujisawa, Tamotsu; Mori, Toshiki; Tsuge, Shoichi; Sato, Toshio Tetrahedron Letters, 1983 , vol. 24, # 14 p. 1543 - 1546

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被引用次数: 41

摘要

Abstract A new method for the direct conversion of carboxylic acids to aldehydes using N, N- dimethylchloromethyleniminium chloride and lithium tri-t-butoxyaluminum hydride was established. This method provides a convenient way for the chemoselective reduction of carboxylic acids even with such a functional group as halide, ester, nitrile, olefin, and ketone.