Chemical Communications

An unusual dianion equivalent from acylsilanes for the synthesis of substituted β-keto esters

CV Galliford, KA Scheidt

文献索引：Galliford, Chris V.; Scheidt, Karl A. Chemical Communications, 2008 , # 16 p. 1926 - 1928

全文：HTML全文

被引用次数: 2

摘要

Using this new process, various unsubstituted β-ketoesters can be prepared rapidly (Table 1, entries 1–5). We were pleased to discover that the substrate scope for the reaction accommodates three different diazo esters, (entries 1, 2 and 5) and both alkyl and aryl acylsilanes (entries 3 and 4). A novel aspect of this new process is the ability to utilize the dianion equivalent in carbon–carbon bond forming reactions. For example, the addition of MeI to the reaction in ...